The four 10-second spots seek to differ Edwards from his rivals by touting the former North Carolina senator's opposition of NAFTA, his refusal to take money from Washington lobbyists, his pledge not to employ lobbyists in the White House, and a recent CNN Poll showing he is the only Democratic presidential candidate to beat all the Republicans in a general election match up.
The commercials follow Edwards' four-day bus tour of the southern state - an important primary contest for him following his distant third-place showing in New Hampshire last week. Edwards, who was born in South Carolina, won the state in 2004. But recent polls suggest he trails Clinton and Obama there by double digits.
The South Carolina Democratic Primary is scheduled for January 26.
– CNN Ticker Producer Alexander Mooney