(CNN) - The Obama campaign launched some of its sharpest attacks to date on Hillary Clinton's candidacy Friday, telling reporters on a conference call that the New York senator is a dishonest politician who has consistently misled voters.
Referencing a new Gallup Poll suggesting 53 percent of Americans don't view Clinton as trustworthy, Obama campaign manager David Plouffe said Clinton would be a "deeply flawed nominee," and suggested it would be "nearly impossible" for her to win a general election.
"She is not seen as trustworthy by the American people," Plouffe said. "She has consistently in this campaign engaged in political calculation to mislead voters....It will nearly be impossible to win a general election if more than half the electorate thinks you're untrustworthy.
"If Sen. Clinton wants to have a discussion about electability and vetting, we're happy to have it," Plouffe also said. "She would be a deeply flawed nominee. There are character issues here that will cause us real problems in the fall."
Plouffe specifically took issue with newly-released Clinton White House schedules that indicate the then-first lady may have been present in several meetings with congressional leaders to promote NAFTA - the trade legislation she now sharply criticizes on the campaign trail. She emphasized her consistency on that position in the days leading up to the March 4 primary contest in Ohio, a state whose Democratic electorate is dominated by union-workers generally opposed to the trade deal."
Sen. Clinton essentially misled the voters of Ohio, strongly suggesting she was always opposed to NAFTA privately," Plouffe said. "But now we see that she had meetings, where the sole purpose was to cheerlead for NAFTA and press for its support."
"Sen. Clinton likes to talk about do-over elections," he added. "The only do-over election we might want to consider is in Ohio, since Sen. Clinton misled the voters in Ohio about her support of NAFTA."
In a memo sent to reporters shortly after Plouffe's comments, Clinton spokesman Phil Singer said, "At this point, it’s no secret that the Obama campaign is in political hot water given the news stories of the last few weeks and is desperate to change the subject."
- CNN Ticker Producer Alexander Mooney