In the weekly Republican radio and Web address, Blackburn said the Presidents plan for energy efficiency will only push the country toward a deeper economic recession.
"If President Obama has his way, the Copenhagen conference will produce mandatory emissions limits that would destroy millions of American jobs and damage our economic competitiveness for decades to come," the Tennessee congresswoman said.
While in Copenhagen, Denmark, next week, Obama is expected to set a goal of reducing emissions to 17 percent below 2005 levels over the next decade.
"Just think of what will happen to small businesses and manufacturers hit with these skyrocketing energy bills," Blackburn added. "With Americans already facing double-digit unemployment, there could not be a worse time to unilaterally disarm our engines of job creation and economic growth."
According to the latest CNN Opinion Research Corporation poll, six in 10 Americans support a "cap and trade" proposal to cut pollution.
Touting her proposed bill H.R. 391, which aims amend the Clean Air Act so greenhouse gases are not subject to the act, Blackburn emphasized the Republicans aren't opposed to energy efficiency.
"Republicans are all for clean water, clean air, and clean energy," Blackburn said. "We just don't think we have to tax people out of their house and home to get there. That's why we have proposed an 'all of the above' energy strategy that says, let's put every clean, responsible energy option on the table so we can create jobs, ease the strain on family budgets, and clean up our environment."