A microphone picked up Biden uttering the "F" word Tuesday in the majestic East Room of the White House, as President Obama signed the historic health care reform bill into law.
After delivering a rousing introduction of the president in which he praised Obama's "perseverance" and "clarity of purpose," Biden turned to embrace his boss.
As the crowd of approximately 300 people cheered wildly, Biden turned to Obama and said with a big smile, "This is a big f-- deal!"
The president did not react to the comment, apparently aware that the microphones may have picked up the words.
Shortly after the ceremony, White House Press Secretary used his Twitter feed to try and diffuse any controversy.
"And yes Mr. Vice President, you're right..." Gibbs tweeted from his @PressSec Twitter account.
An aide to the vice president pointed reporters seeking comment to Gibb's tweet.
The vice president is known for unscripted moments, but not in such a high-profile setting as a bill-signing ceremony in the East Room. According to the White House Historical Association, first lady Abigail Adams was famous for using the room to dry her laundry. President John F. Kennedy lay in state in the East Room after his assassination in 1963.