(CNN) - Christine O'Donnell's upset win over Rep. Mike Castle in the Delaware Republican Senate primary is also another major victory for the Tea Party Express and for Sarah Palin.
"I also want to thank the Tea Party Express," said O'Donnell in her victory speech Tuesday night.
The Tea Party Express, a leading Tea Party organization, endorsed O'Donnell on July 21 and spent more than $250,000 to help the once long shot candidate defeat Castle, a brand name in Delaware thanks to two terms as governor and the past 18 years as the statewide congressman.
O'Donnell's victory comes two weeks after Sen. Lisa Murkowski conceded to Joe Miller in Alaska's GOP Senate primary. The Tea Party Express pumped in about $600,000 to help the once unknown Miller edge out Murkowski, part of a political dynasty in Alaska.
(CNN) – CNN senior political analyst David Gergen said Tea Party favorite Christine O'Donnell's Delaware upset could spell trouble for the Republican Party.
O'Donnell knocked off former governor and nine-time U.S. Rep. Mike Castle in the GOP Senate primary on Tuesday.
"It's the clearest rebellion we've had all season. The biggest anti-establishment vote that's occurring against Republican candidates," Gergen said.
"One clear result out of Delaware is the chances of Republicans now gaining the Senate have gone down significantly. Delaware was an automatic pickup for Republicans before Mike Castle went down," he said.
New York (CNN) - He's served in Congress for almost 40 years, but Tuesday's primary in New York was unlike any other for Democratic Congressman Charles Rangel.
The 80-year-old Rangel, facing five challengers and 13 ethics allegations in the House, came out on top in the Democratic primary for New York's 15th district, CNN has projected.
On the eve of the primary, robocalls using former President Bill Clinton's voice went out telling voters: "We need Charlie to go back to Washington, to work with President Obama to say, 'Yes.' "
Despite the ethics allegations, support still poured in for Rangel because "he's been a great congressman for Harlem," said Democratic strategist and CNN contributor Paul Begala.
Is Democratic Rep. Charlie Rangel in for the fight of his life? It depends who you ask.
The 20-term New York incumbent, plagued by ethics charges, faces five challengers in the Democratic primary.
Redstate.com editor Erick Erickson told CNN that while the national media might paint the race as a tight one, the local press thinks Rangel is a safe bet.
"I've talked to a number of people who live in NY-15, his district, and no one there thinks he's going to be thrown out," he said. "Everyone it seems like in Washington and people I've talked to outside of his district think he's probably in for a fight for his life, but I know very few people who live in or around his district who think that."
Editor's note: Look for regular Trail Running field updates from CNN's anchors, correspondents and producers spread out across the country covering politics on the campaign trail. As always, the CNN Political Ticker is your source for up-to-the-minute political news– now even more so.
11:01 p.m. - It's been a long time since I parachuted in to watch an election night event at the headquarters of a famous politician under a cloud.
But it all came back to me in Harlem where New York Rep. Charlie Rangel was asking voters to send him on to compete for a 21st term in the Congress as a Democrat even though he was facing 13 ethics charges back in Washington.
A handful of big names in the Democratic establishment turned out including Gov. David Patterson and former NY mayor David Dinkins. What ethics charges? They talked about all Rangel has done for New York.
CNN is projecting tea party challenger Carl Paladino the upset winner over Rick Lazio in New York Republican gubernatorial primary.
(CNN) - Jim DeMint's political operation is firing back at anonymous Senate Republican aides who criticized the conservative South Carolina Senator on Tuesday night for helping Christine O'Donnell capture the GOP Senate nomination in Delaware, possibly jeopardizing the party's chances of winning the seat in November.
One unnamed senior GOP aide told CNN's Dana Bash: "I wonder who Harry Reid and Chuck Schumer are calling first tonight - Chris Coons for becoming the next Senator from Delaware or Jim DeMint for helping to make it happen.
Another GOP leadership aide griped to Hotline On Call that "DeMint is not interested in a majority, he'd rather establish himself as the leader on the fringe."
DeMint's Senate Conservatives Fund directed money to O'Donnell's campaign and numerous other conservative Senate hopefuls who knocked off establishment-backed candidates in GOP primaries this cycle.
Washington (CNN) - House Democratic leaders returned to the Capitol and used their first closed door meeting Tuesday night with rank and file Democrats to try to calm jittery nerves by delivering a series of presentations making the case that things aren't as dire for Democrats as they seem, according to multiple sources in the room.
They also heard from Democratic pollster Stan Greenberg, who made the case that the Democrats push to extend tax cuts only for the middle class and below is their bet against Republicans.
House Speaker Nancy Pelosi offered a preview of her private remarks before going in, insisting to reporters that she stands by her prediction that Democrats will hold control of the House.
"I am not yielding one grain of sand. I want to have the same big strong majority we have but I feel certain that we will," said Pelosi, responding to a question from CNN about whether she still thinks they will keep the majority.
(CNN) - Shortly after Tea Party-backed Christine O'Donnell had been projected as the winner over establishment candidate Mike Castle in the Delaware Republican Senate primary, the National Republican Senatorial Committee issued this statement:
"We congratulate Christine O'Donnell for her nomination this evening after a hard-fought primary campaign in Delaware." – Rob Jesmer, NRSC executive director
"Usually, there's a second sentence in statements like these," said CNN Political Producer Peter Hamby, in which the committee promises to campaign for the party's candidate.
"The NRSC statement appears as tepid as the Republican Governors Association's initial statement following Rick Scott's victory in Florida," said CNN Deputy Political Director Paul Steinhauser.
Outsider Scott defeated party favorite Bill McCollum in August in Florida's gubernatorial primary.
(CNN) – Do not expect national Republicans to rally around Christine O'Donnell and infuse much needed campaign cash into her campaign for Delaware's open Senate seat. The Tea Party favorite upset establishment backed Rep. Mike Castle Tuesday evening, and GOP officials are concerned that O'Donnell has no chance of winning the seat – once held by Vice President Biden for 26 years – in November.
"Until she demonstrates some viability in the polls we are not going to have any money for her," a top Republican official told CNN. "It is now incumbent on Sarah Palin, Jim DeMint and the Tea Party Express to help support her. They got her here. Now make it happen."