(CNN) - Incumbent Alaska Sen. Lisa Murkowski, who launched a write-in campaign for re-election after losing the Republican primary, believes the race in Alaska will be closer to resolution by the end of this weekend but added that her opponent, Tea Party-backed Republican Joe Miller, is working to "disenfranchise" voters.
Miller vote-count observers are challenging ballots that misspell the senator's name – or, in some cases, spell it correctly but aren't written clearly.
"When you make challenges like this, you are working to disenfranchise that voter," Murkowski said on CNN's John King, USA. "It is clear what that voter's intent was. The intent was to vote for Lisa Murkowski."
Miller filed a lawsuit earlier this week to ensure a complete audit of all ballots counted, but Murkowski remains confident and critical of her challenger.
"Miller doesn't know what to do with the fact that people actually did what they were supposed to do," Murkowski told CNN Chief National Correspondent John King. "What we're seeing now, I believe, quite honestly are acts of desperation."
She also addressed earlier comments by South Carolina Sen. Jim DeMint, who supported Miller. DeMint said he and Murkowski will have "some making up to do" if she returns to the Senate.
"He has suggested that he's got some making up to do," Murkowski said. "I'll let him make that first move."