"I expect my opponents to go back 15, 20, 25 years and try to render an alternate judgment I understand that's what they'll do," the former House Speaker told WRKO radio host Howie Carr, referring to his previous marital infidelity and how it might affect a bid for the Republican presidential nomination.
Gingrich, who has been married three times and admitted to past infidelities, responded to criticism he sidestepped responsibility for his affairs in an interview with CBN reporter David Brody last week. Gingrich told Brody he was "partially driven by how passionately I felt about this country, that I worked far too hard and things happened in my life that were not appropriate."
During Monday night's WRKO interview, Gingrich said, "I'm not blaming my life on anyone, and I'm not offering excuses."
"I've made no bones about the fact there were times I did the wrong thing, and I've made no bones about the fact that I've asked for forgiveness," Gingrich said.
There is at least one potential 2012 GOP presidential opponent who is already weighing in as to how Gingrich's past will play into the campaign.
Former Pennsylvania Sen. Rick Santorum said in a interview with National Review Online earlier this week that Gingrich's personal history, while relevant, should not be the main focus.
"He, like we all do, will have to account for our past decisions. People will take (his past) as a legitimate issue to consider, as to how it would affect his ability to do his job," Santorum said. "I am not saying that is not a legitimate question, but it's not an issue with respect to the positions he takes."
Gingrich was upbeat on how voters would ultimately judge his fitness for office.
"I think most Americans are fair," he said. "And I think most Americans will look at the totality of my life."