(CNN) - President Barack Obama is the target of a new ad from American Crossroads, an independent Republican advocacy group, which attacks the president's economic policies ahead of his trip to St. Louis Tuesday.
The 30-second spot juxtaposes Obama's past comments about not raising taxes with news accounts of his jobs plan that, if passed, would add one and half trillion dollars in new tax revenue.
It also quotes former President Bill Clinton saying raising taxes will not solve the country's economic woes and Velma Hart who notoriously told the president that she was "exhausted of defending you" at a town hall in 2010.
"He raised our hopes. He seemed to understand … But today he's different," the ad says. "President Obama's latest way is still the wrong way."
The commercial that Crossroads said started airing Monday night, will run through Wednesday in St. Louis on cable television, including on CNN and Fox News with a total buy of $50,000. Not coincidentally, Obama will travel to St. Louis Tuesday afternoon to deliver remarks at two campaign events in The Show Me State.
"The ad will serve to provide a counterpoint before, during and after the president's visit to St. Louis as he sells his tax increase and re-election," Jonathan Collegio, spokesman for American Crossroads, said in a statement.
American Crossroads, a group founded by Karl Rove and led by former Republican National Committee Chairman Mike Duncan, spent $70 million in the 2010 midterm elections and has pledged to raise $120 million for the 2012 cycle.
They also embarked Tuesday on a new paid web video campaign on Yahoo intended to counter Obama's online interview with Yahoo News/ABC online Monday. Over the next week, viewers will see the same Crossroads ad that is running in Missouri before the interview rolls on the Yahoo website.
"Our goal is to keep Obama on defense, where he's unable to generate an unchallenged media hit to sell his tax increase or his re-election," Crossroads President Steven Law said in a statement.
Brad Woodhouse, communications director for the Democratic National Committee, said the ad is a sign Republicans are siding with the interests of the "super wealthy."
"While Karl Rove and the Republican field yearn for the failed policies of the past, President Obama is fighting to create jobs and put money back in the pockets of middle class Americans and small businesses," Woodhouse said. "Like the President, Republicans should put politics aside – reject the divisive politics of Karl Rove – and work with President Obama to move the country forward."
Priorities USA Action, an independent group that backs Democratic candidates, criticized the Republican PAC for false advertising.
“Mitt Romney, Rick Perry, and Karl Rove will spend millions on false television ads because they know that the American public strongly supports the President's plan that will finally ensure billionaires do not pay a lower tax rate than middle class families,” Priorities USA senior strategist Bill Burton said in a statement.