(CNN) - The Democratic National Committee will run a newspaper ad in Detroit on Wednesday, targeting Mitt Romney as the GOP presidential front-runner arrives for a debate at Oakland University.
The ad highlights a statement Romney made in a 2008 op-ed titled "Let Detroit go Bankrupt," predicting the auto industry bailouts would be detrimental to the economy.
"If General Motors, Ford and Chrysler get the bailout that their chief executives asked for yesterday, you can kiss the American automotive industry goodbye," Romney wrote in The New York Times on November 18, 2008. "It won't go overnight, but its demise will be virtually guaranteed."
The newspaper ad includes the quote and uses the title of the piece, saying "What was Mitt Romney's plan for Michigan's automobile industry? 'Let Detroit go bankrupt'."
The ad is part of a series of DNC efforts aimed at pinning Romney on his statements about Detroit, in addition to comments he made about the housing foreclosure industry, in which he said the best way to solve the problem is to let it "run its course."
Brad Woodhouse, spokesman for the DNC, pointed out in a statement that the bailouts saved "1.4 million jobs up and down the auto supply chain."
"If Mitt Romney had had his way – those jobs would have gone up in a puff of smoke," Woodhouse wrote.
Romney's team has previously responded to the DNC's campaigns against him, arguing their attacks only show Democratic fears that Romney will become the GOP nominee.
"Democrats realize that Mitt Romney is the only Republican who can defeat President Obama in 2012. They are desperate to hold onto power, and will do and say anything to distract from President Obama's abysmal economic record," Romney campaign spokesman Ryan Williams recently told CNN.
Romney is set to face off in a CNBC presidential debate with seven other Republican candidates at Oakland University on Wednesday night.