(CNN) - Sen. Thad Cochran, R-Mississippi, will run for a seventh term next year, his spokesman Chris Gallegos confirmed to CNN.
Until Friday, it was unclear whether the longtime Senator would try to keep his seat. Cochran, who turns 76 on Saturday, already faces a primary challenger in conservative state Senator Chris McDaniel.
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Cochran is one of several incumbent Republicans facing challenges from the right. Sen. Pat Roberts of Kansas, Sen. Lindsey Graham of South Carolina, Sen. Mike Enzi of Wyoming, Sen. Lamar Alexander of Tennessee, and Senate Minority Leader Mitch McConnell of Kentucky all have announced opponents in their respective GOP primaries.
The Senator's decision was first reported by Gannett.
"I'm comfortable with my decision," Cochran told the news outlet. "I'm looking forward to it. People have been very generous and expressed appreciation. Some have even started sending contributions and helping in that way.
In a statement, McDaniel said Cochran has "had a long and distinguished career representing the people of Mississippi."
"I look forward to a positive campaign based on the future of our state, our country and the Republican Party," he said. "As a strong conservative, I will fight to bring those values to Washington."
– CNN's Dana Bash contributed to this report.