Updated 8:15 p.m. ET, 1/8/2014
Washington (CNN) - Two longtime House Democrats–Rep. Carolyn McCarthy of New York and Rep. Mike McIntyre of North Carolina–announced Wednesday they won't seek re-election in November.
Their decisions bring the total number of House Democratic retirements to three. On the other side of the aisle, nine House Republicans have announced they're retiring after 2014.
Democrats need to net 17 seats in order to win back the House.
McCarthy said Wednesday in a statement she won't run for a 10th term representing her district in Long Island.
"I am very proud of the many accomplishments my colleagues and I have achieved, and am grateful to my family, my staff and all the countless volunteers and supporters with whom I have worked during my time in office," McCarthy said in a statement.
The congresswoman has been on a leave of absence lately as she undergoes treatment for cancer.
McCarthy got her start in politics by lobbying for gun control after her husband was killed and her son was injured in the Long Island Railroad Massacre of 1993. She was elected to office three years later.
President Barack Obama thanked McCarthy for her service, praising her as a "principled and compassionate" leader.
"In particular, she’s been at the forefront of the issue that brought her to Washington seventeen years ago: reducing and preventing gun violence. She was also instrumental in the passage of the Dodd-Frank Wall Street Reform Act to prevent future financial crises and has been a leading advocate for improving education, especially college affordability," Obama said in a statement.
After her announcement, the nonpartisan political handicapper Cook Political Report moved her district, NY-4, from a "solid" Democratic district to "leaning" Democratic.
Another political handicapper, The Rothenberg Political Report, predicts the district will remain "safe" for Democrats for now.
Rep. Steve Israel of New York, the chairman of the Democratic Congressional Campaign Committee, praised McCarthy and said that "Carolyn's successor will have big shoes to fill. We are confident that the people of this strongly Democratic seat will choose a replacement who will follow Carolyn's tradition of putting middle class families first and fighting for the safety of our schools and neighborhoods."
Andrea Bozek, a spokeswoman for the National Republican Congressional Committee, described the New York seat as "competitive."
Like McCarthy, McIntyre is also in his ninth term and won't run for re-election.
"My family and I are ready for a new chapter and excited about new opportunities to continue helping North Carolina," he said in a statement.
A Blue Dog Democrat, he's one of just a few white Southern Democrats remaining in Congress and tends to lean to the right on social issues.
McIntyre's district, NC-7, had been redrawn after the 2010 census to favor Republicans, and he barely survived re-election in 2012. His race against Republican David Rouzer went into a recount that lasted several weeks after Election Day. Rouzer ultimately conceded.
In a statement on McIntyre's retirement, Obama called the congressman a "strong advocate for our men and women in uniform and a key voice on issues that shape the lives of Americans in rural communities."
The Republican is challenging McIntyre again this year and released a statement praising the congressman as a "tireless advocate" for the district. He also vowed to work hard to win the seat this year.
"After falling just a handful of votes short in 2012, it is with great optimism that my supporters and I continue our mission to bring conservative leadership to Southeastern North Carolina," he said.
With McIntyre's retirement, NRCC Chairman Greg Walden, said McIntyre's retirement "solidifies the extremely difficult road ahead for Democrats in 2014."
"This retirement announcement also proves that ObamaCare and its negative impact continues to burden Democrats in 2014 – even for Democrats who voted against the law like McIntyre and Matheson," Walden argued.
The Cook Political Report changed its prediction of the race from "leaning" Democrat" to a "likely" win for Republicans.
For its part, The Rothenberg Political Report changed its prediction from a "pure toss-up" to a race being "safe" for Republicans.