(CNN) - The Clintons and the Bushes aren't the only families with an extended presence in American presidential politics.
That's a piece of history Hillary Clinton was sure to note in an interview published Tuesday in Germany's Der Spiegel when asked if America will turn into a monarchy if she or Jeb Bush were to win the presidency in 2016 (should either decide to run).
"We had two Roosevelts. We had two Adams," Clinton said, adding "It may be that certain families just have a sense of commitment or even a predisposition to want to be in politics."
"I ran for president, as you remember. I lost to somebody named Barack Obama, so I don't think there is any guarantee in American politics. My last name did not help me in the end," she said. "Our system is open to everyone. It is not a monarchy in which I wake up in the morning and abdicate in favor of my son."
If Bush ran and won in 2016, he would be the third Bush in the White House over the past three decades. And if Clinton ran and won the next election, she would be the second President Clinton in the White House in the past two decades, after her husband.
As Clinton weighs whether to launch a campaign for the White House in 2016, her name recognition - as former first lady, as well as secretary of state and senator - has been a double-edged sword.
Her global popularity helped during her time as America's top diplomat and will undoubtedly spur book sales as she continues the European leg of her book tour for "Hard Choices." But being such a longtime figure in U.S. politics might also prove to be a negative if she runs for president as Americans' trust in Washington falters.
Jeb Bush, the former Florida governor, is also considering a run for the White House. Should he run, he has the support of his family - including his father, Bush 41, and his brother, Bush 43 - but his mother, Barbara Bush, has expressed reservations about having another Bush in the White House.
She said in an interview earlier this year "I think this is a great American country, and if we can't find more than two or three families to run for high office, that's silly."
Bush has joked about his mother's comments, but also discussed how his family name may hurt him as much as help him if he decides to run for the White House in 2016.
And a majority of Americans agree with Mrs. Bush. Sixty-nine percent of people questioned in a NBC News/WSJ poll conducted in April said there should be more diversity in families in the White House.
CNN Political Editor Paul Steinhauser contributed to this report.