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Matt Damon stars in the ONE Campaign's latest ad 'Voices'.

(CNN)—The ONE campaign released a star-studded pre-convention ad Thursday, featuring Michelle Obama and Cindy McCain, the wives of both presumptive presidential nominees.

The 30-second spot, ‘'Voices,’ stars actor Matt Damon, who has traveled with the ONE campaign to Africa two times. As the ad progresses, Damon remains on camera, but his voice is replaced by those of New York Mayor Michael Bloomberg, Michelle Obama, Cindy McCain, as well as average Americans.

"“Thanks to everyday Americans who chose to make a difference millions of lives have been saved in the world’s poorest countries,” Damon says. “But there’s still more to do,” Cindy McCain adds. “Please join the millions of Americans from every party,” Damon continues. “Who are coming together as ONE,” says Michelle Obama.

The nearly $2 million ad campaign emphasizes the need for the United States to be educated and involved in helping some of the world's most deprived countries.

Michelle Obama and Cindy McCain have been active supporters of the campaign's mission. In July, Mrs. McCain joined the ONE Campaign on a trip to Rwanda, visiting health clinics, and an orphanage.

The ad will hit the airwaves Sunday, August 24 on cable and entertainment channels.

Full script after the jump

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Mayor Bloomberg introduced Sen. Obama at an event in New York City in March.

(CNN) - New York City Mayor Michael Bloomberg blasted unfounded e-mail speculation over Barack Obama’s religion today, calling them “lies” and “wedge politics at its worst,” according to prepared remarks released by his office.

“Of course, in any election, one candidate’s supporters will look to pick holes in the other candidate’s statements – on Israel and everything else. And that’s fine. …,” Bloomberg said in Boca Raton. “But as we do that, let’s make sure that we, as Jews and as voters, keep the conversation focused on the facts and not let it descend into false rumor and innuendo.

“Unfortunately, we’ve already seen that happen. As I’m sure many of you know, there are plenty of emails floating around the Internet targeting Jewish voters and saying that Senator Obama is secretly a Muslim, and a radical one at that. Let’s call those rumors what they are: Lies.”

“They are cloaked in concern for Israel, but the real concern is about partisan politics. Israel is just being used as a pawn, which is not that surprising, since some people are willing to stoop to any level to win an election."

Bloomberg, who has been the object of both presidential and vice presidential speculation this election cycle, also praised McCain for denouncing the rumors.

Earlier this month, both Obama and McCain rejected a proposal by the Independent mayor for a joint townhall to be held in the city.

CNN=Politics Daily is The Best Political Podcast from the Best Political Team.

Washington (CNN) - In the latest episode of CNN=Politics Daily, CNN's daily video political podcast, the dynamics of the 2008 presidential race take center stage.

Suzanne Malveaux reports on Sen. John Kerry's endorsement of Sen. Barack Obama.

New Mexico Gov. Bill Richardson announced Thursday that he was ending his presidential bid after disappointing results in the Iowa caucuses and the New Hampshire primaries. Wolf Blitzer speaks with Richardson about his decision to bow out. Dan Lothian also takes a look at the trend of more experienced candidates not faring well as well as their less experienced rivals so far in the 2008 presidential race.

Allan Chernoff reports on the mortgage crisis and how it may impact the White House race.

Will New York City Mayor Michael Bloomberg join the presidential race? Senior Political Analyst Bill Schneider takes a look at how Bloomberg's entry might impact the 2008 race and potentially hurt the Democratic Party's chances of retaking 1600 Pennsylvania Avenue.

Finally, Wolf Blitzer tells you which headlines on CNN's Political Ticker are drawing the most comments from readers.

Click here to subscribe to CNN=Politics Daily.

–CNN Associate Producer Martina Stewart

WASHINGTON (CNN) - It's New Years Eve and a hard-fought year of campaigning by the field of White House hopefuls will finally be subjected to its first test with Iowa's caucuses on January 3.

In Monday's Best Political Podcast, Dana Bash reports on Mike Huckabee's last-minute decision not to air an attack ad.

Senior Political Analyst Bill Schneider explains why Iowa may be make-or-break for one GOP and one Democratic front-runner and Senior Political Correspondent Candy Crowley reports from the Hawkeye State about the Democrats' unprecedented get-out-the vote effort for the caucuses.

Wolf Blitzer speaks with Mitt Romney about Huckabee's decision to stay positive on the eve of the voting in Iowa and Blitzer also shares with you the hottest stories on the Political Ticker.

Click here to subscribe to The Best Political Podcast.

–CNN Associate Producer Martina Stewart