Sen. Kennedy has endorsed Sen. Barack Obama for the Democratic presidential nomination.

BOSTON, Massachusetts (CNN) – The hospital treating Sen. Edward Kennedy said Tuesday that the Democratic senator has a malignant brain tumor.

The tumor was the cause of his seizure on Saturday, according to a statement from the doctors treating the 76-year-old at Massachusetts General Hospital.

While such tumors are usually treated by a combination of radiation and chemotherapy, Kennedy's doctors said "decisions regarding the best course of treatment for Senator Kennedy will be determined after further testing and analysis."

"Senator Kennedy will remain at Massachusetts General Hospital for the next couple of days according to routine protocol."

Kennedy "remains in good overall condition and is up and walking around the hospital," the statement said.

He was airlifted to Massachusetts General Hospital on Saturday, and has remained hospitalized since then.

(updated with additional information 1:30 p.m.; full hospital statement after the jump)

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Sen. Kennedy seems to be out of any 'immediate danger,' doctors say.

BOSTON, Massachusetts (CNN) — Doctors at Massachusetts General Hospital Sunday were trying to determine the cause of Sen. Edward Kennedy's seizure.

Medical officials said the 76-year-old Democratic icon was in serious condition but seemed to be out of any "immediate danger."

Preliminary tests Saturday night determined Kennedy had not suffered a stroke, a physician at the hospital said.

Kennedy was flown to the hospital on a medical jet Saturday.

"Over the next couple of days, Sen. Kennedy will undergo further evaluation to determine the cause of the seizure, and a course of treatment will be determined at that time," said Dr. Larry Ronan, Kennedy's primary care physician. He added that Kennedy was "resting comfortably and watching the Red Sox game with his family."

Doctors offered no update Sunday morning.

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Sen. Kennedy, D-Massachusetts.

(CNN) — Sen. Edward Kennedy was hospitalized in Boston, Massachusetts, after suffering an apparent seizure Saturday morning, his family said.

"He is undergoing a battery of tests at Massachusetts General Hospital to determine the cause of the seizure. Sen. Kennedy is resting comfortably, and it is unlikely we will know anything more for the next 48 hours," a statement from his office said.

Senate Majority Leader Harry Reid said Saturday he spoke to the wife of the Massachussetts Democrat, Vicki, and that she told him that her husband is going to be fine.

"Everyone knows he is a strong fighter," Reid said, speaking at the Nevada state Democratic Party convention.

Kennedy was transferred to Massachusetts General Hospital in Boston for evaluation after initial treatment at Cape Cod Hospital, an earlier statement from his office said.

The senator spent less than an hour in the Cape Cod facility, hospital spokesman David Reilly said.

Earlier, a well-informed Democratic source in Massachusetts said the 76-year-old senator had "symptoms of a stroke" at the Kennedy family compound in Hyannis Port.

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WASHINGTON (CNN) — Sens. Barack Obama, Hillary Clinton and John McCain responded Saturday regarding Senator Ted Kennedy's hospitalization earlier in the day.

Obama, who won the endorsement of the Masachuessets senator, said that his "thoughts and prayers" are with the senator, who was rushed to the hospital earlier Saturday.

At a campaign event in Eugene Oregon, Sen. Obama told his audience: “You know as I have said many times before, Ted Kennedy is a giant in American political history - he has done more for the health care of others than just about anybody in history and so we are going to be rooting for him.”

Clinton, meanwhile, released a statement on Kennedy.

"My thoughts and prayers are with Ted Kennedy and his family today. We all wish him well and a quick recovery."

Later at a campaign picnic at Laredo in Kentucky, Sen. Clinton said of Kennedy…” Nobody has fought harder to make sure everybody got good health care and I know that we all join together in wishing him well."

In a press release, McCain said he was "very sorry to hear that Senator Kennedy has taken ill, and like millions of Americans, Cindy and I anxiously await word of his condition."

"Senator Kennedy's role in the U.S. Senate cannot be overstated. He is a legendary lawmaker, and I have the highest respect for him. When we have worked together, he has been a skillful, fair and generous partner. I consider it a great privilege to call him my friend. Cindy and I are praying for our friend, his wife, Vicki and the Kennedy family," he added.