[cnn-photo-caption image= http://i2.cdn.turner.com/cnn/2008/images/09/27/art.split.gi.jpg caption="Next up: Sen. Biden will debate Gov. Palin."]
(CNN) - Now that Sens. Barack Obama and John McCain have their first presidential debate out of the way, the focus turns to their running mates.
Sen. Joe Biden and Gov. Sarah Palin will face off Thursday at Washington University in St. Louis, Missouri.
There's a lot of anticipation surrounding the VP debate because Palin has remained largely on script in her first month on the campaign trail.
Watch: Europe reacts to U.S. debate
While Biden has a well-earned reputation for impetuous and brutally honest remarks, he's also a long-time senator with decades of experience in the public eye.
As chairman of the Senate Committee on Foreign Relations, the 65-year-old Delaware senator is well versed on foreign policy.
Biden has done nearly 100 interviews since being picked as Obama's VP on August 23.
Palin, on the other hand, did her third interview with a national television network last week. On Wednesday, she held her first media availability with her traveling reporters.