[cnn-photo-caption image= http://i2.cdn.turner.com/cnn/2008/images/11/20/art.napolitano.gi.jpg caption="Napolitano is Obama's choice for Homeland Security Secretary, sources say."](CNN) - President-elect Barack Obama's top choice for secretary of homeland security is Arizona Gov. Janet Napolitano, multiple Democratic sources close to the transition told CNN on condition of anonymity.
One source said he believed the final decision depends on the vetting of the Democratic governor, much like the selection of Eric Holder for attorney general.
Also, multiple Democratic sources say billionaire Chicago businesswoman Penny Pritzker is Obama's leading choice for commerce secretary. Pritzker ran Barack Obama's record-breaking fundraising effort, serving as the campaign's finance chair.
The sources say she would accept the job, which would not be formally offered until vetting is complete. But whether the rigors of the particular Obama vetting process will present a challenge to a business woman with no record in public office - and presumably extensive financial holdings - was