Washington (CNN) - Republicans didn't waste much time in trying to score some political points off of Tuesday's loss by Marjorie Margolies in her bid to re-capture the House seat she lost 20 years ago.
Margolies, the mother-in-law to Chelsea Clinton, was handily defeated as she ran in the Democratic Primary for Pennsylvania's 13th Congressional District. State Representative Brendan Boyle soundly defeated Margolies by 13-percentage points.
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After the seat became open, Margolies decided to try to make a political comeback. She was a freshman member of Congress when she cast a politically risk tie-breaking vote in 1993 allowing then President Bill Clinton's major economic program to barely pass the House. She came from a Republican-leaning district at the time and faced a firestorm of criticism for that vote. She was defeated the next year, 1994, when seeking re-election.
Since that time, Margolies and the Clintons relationship continued but evolved as her son, Marc, and Chelsea dated and then married in 2010. Now they are going to be co-grandparents as the couple is expecting their first child this fall.
Minutes after the race was called Tuesday night, the pro-GOP opposition research shop America Rising blasted out a post titled "Clinton Coattails #Fail."
"Bye-Bye Marjorie" read a Republican National Committee email sent out to reporters Wednesday. "Despite a full-court press from Bill and Hillary Clinton, last night Marjorie Margolies suffered a double-digit primary defeat." The email was accompanied by a list of stories recounting the Clintons' efforts on behalf of Margolies.
Bill Clinton held an event with Margolies in the district in April. The former president was also featured in the campaign's final television ad and recorded a robocall trying to help get the vote for her.
"Twenty years ago Marjorie cast the deciding vote on my economic plan," Bill Clinton said in the campaign robocall. "This is an important election. And I know if you'll send Marjorie to Congress she'll make you proud. So please, on Tuesday go to the polls."
Separately, Hillary Clinton headlined a fundraiser for Margolies in New York last week – one in which the candidate actually did not appear so she could campaign in the district.
Democrats don't believe her loss will have any negative impact on the Clintons and their political reputation. "Somewhere below zero," is how former Bill Clinton adviser Paul Begala put it.
In an interview last week with CNN Chief Political Analyst Gloria Borger, Margolies acknowledged there would be criticism no matter what the Clintons did on her behalf.
"We always knew that if they came in too much we would be blamed for their coming in too much. If they don't come in enough that people would would say they didn't come in enough," Margolies said. "You're kind of damned if you do, damned if you don't. They have done everything we've asked them to do, and I am running on what I have accomplished in the last 20 years and not on my affiliation with the Clintons."
A different opponent of Margolies, Daylin Leach, put up a tv ad criticizing her use of Bill Clinton. "While some cling to the past we just can't go backwards," the candidate's young daughter said in the commercial.
Margollies had been criticized for not campaigning robustly enough early in her candidacy when she was the frontrunner because she had the name recognition. She then participated in more debates. In recent weeks some of her opponents had alleged she had misused some of her campaign funds which she strenuously denied.
“Bill Clinton proved no big help – when she did not make a compelling case herself for re-election,” Terry Madonna, a professor at Franklin and Marshall College in Lancaster, Pennsylvania, told CNN.